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Growth HormonePreliminary grade

Tesamorelin + Ipamorelin

Tesa/Ipa blend

The FDA-approved GHRH leg paired with Ipamorelin — stronger scientific pedigree than CJC/Ipa, less commonly compounded.

Verdict — C · Emerging / Mixed

A logical upgrade for buyers who want the FDA-validated GHRH leg — stronger evidence pedigree than CJC/Ipa but less available and more expensive. Component-derived evidence only; obtain from a pharmacy with a valid COA for both components.

PepScore / 100

CEmerging / Mixed

How we compute this →

Overview

The Tesamorelin + Ipamorelin stack pairs the only FDA-approved GHRH analogue (Egrifta) with the selective GHRP Ipamorelin, providing a validated GHRH signal alongside a clean GH-pulse amplifier. The rationale is the same as CJC/Ipa but with a higher-evidence GHRH component. This combination is less commonly compounded than CJC/Ipa and there is no fixed-blend RCT; all evidence is component-derived. Tesamorelin's glucose/IGF-1 implications carry over from the individual compound.

PepScore Breakdown — the four axes

Evidence

35% weight

57/100

How strong is the published human science?

Human data depth20/40

Regulatory & registry status16/30

Reproducibility & consistency13/20

Mechanism characterized in humans8/10

Sourcing & COA

30% weightOur moat

59/100

Can a buyer obtain an independently-verified, high-purity version? — our proprietary layer.

Independent 3rd-party testing20/35

Verified purity %18/30

COA transparency & batch traceability12/20

Multi-vendor verified availability9/15

Safety & Risk

25% weight

69/100

What is the real-world harm potential?

Documented AEs / toxicity28/40

Contraindication breadth17/25

Regulatory warnings13/20

Therapeutic index / margin11/15

Practicality

10% weight

67/100

How easy is it to actually run a verified version?

Verified-source availability22/35

Cost / value per cycle16/25

Reconstitution & administration20/25

Storage & stability9/15

Sources & Citations

Every claim cites a primary source. Citations are machine-audited against NCBI — see methodology.

Want a clinical path?

Talk to a licensed provider about Tesamorelin + Ipamorelin and whether it's appropriate for your situation.

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Telehealth. Not medical advice — for educational purposes.

PepScore62/100 · C

Last gradedJune 28, 2026

Next re-grade triggerWider compounding availability and a head-to-head study vs CJC/Ipa would move the grade.

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Educational only — not medical advice. PepScore is an educational research grade, not a prescription or dosing recommendation. Some vendor links are affiliate links — this never affects grades. Consult a licensed healthcare provider before using any compound.