CognitivePreliminary grade

Selank

A Russian-developed anxiolytic/nootropic peptide with a domestic regulatory record but little Western trial evidence.

Verdict — C · Emerging / Mixed

A reasonably benign anxiolytic peptide with a Russian regulatory track record, but the evidence base barely extends beyond domestic studies and sourcing is unverified. A C — interesting and low-burden for the experienced, not a settled recommendation.

PepScore / 100

CEmerging / Mixed

How we compute this →

Overview

Selank is a synthetic heptapeptide derived from the immunomodulator tuftsin, developed in Russia as an anxiolytic with reported nootropic and immunotropic effects. It carries a Russian regulatory registration and a small domestic clinical literature suggesting benefit in anxiety, but it has essentially no Western registered-trial evidence and the human data are limited and hard to reproduce internationally. Tolerability appears good in the available studies; sourcing is research-grade and COA verification is the limiting factor.

PepScore Breakdown — the four axes

Evidence

35% weight

49/100

How strong is the published human science?

Human data depth16/40

Regulatory & registry status14/30

Reproducibility & consistency11/20

Mechanism characterized in humans8/10

Sourcing & COA

30% weightOur moat

56/100

Can a buyer obtain an independently-verified, high-purity version? — our proprietary layer.

Independent 3rd-party testing18/35

Verified purity %17/30

COA transparency & batch traceability11/20

Multi-vendor verified availability10/15

Safety & Risk

25% weight

73/100

What is the real-world harm potential?

Documented AEs / toxicity30/40

Contraindication breadth18/25

Regulatory warnings13/20

Therapeutic index / margin12/15

Practicality

10% weight

66/100

How easy is it to actually run a verified version?

Verified-source availability22/35

Cost / value per cycle17/25

Reconstitution & administration18/25

Storage & stability9/15

Sources & Citations

Every claim cites a primary source. Citations are machine-audited against NCBI — see methodology.

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PepScore59/100 · C

Last gradedJune 28, 2026

Next re-grade triggerA Western registered trial or a clean multi-vendor COA sweep would lift the grade.

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