PepEvolutionMazdutide
China-approved dual GLP-1/glucagon agonist (NMPA 2025), robust GLORY program data, very limited Western sourcing.
Verdict, C · Emerging / Mixed
NMPA-approved with strong phase-3 data, but Western availability is near-zero and any gray-market material should be treated with high skepticism. A China-validated compound with limited reach outside that market today.
Overview
Mazdutide (IBI362, Innovent Biologics) is a dual GLP-1/glucagon receptor agonist that received NMPA approval in China in 2025 for weight management following the GLORY phase-3 program. Phase-3 data show approximately 16-18% weight loss. Western regulatory approval has not been sought; sourcing outside mainland China is essentially unverified.
PepScore Breakdown, the four axes
Evidence
35% weightHow strong is the published human science?
Sourcing & COA
30% weightOur moatCan a buyer obtain an independently-verified, high-purity version?, our proprietary layer.
Safety & Risk
25% weightWhat is the real-world harm potential?
Practicality
10% weightHow easy is it to actually run a verified version?
Sources & Citations
Every claim cites a primary source. Citations are machine-audited against NCBI, see methodology.
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